Flexible Purification Solutions from Process Development to Commercialization
Our industry-leading bioseparation technologies empower our customers to deliver life-improving and life-saving advanced therapies to patients worldwide. With a legacy of over 30 years, our team takes pride in supplying world-class products that adhere to FDA and EMA standards, ensuring excellence in manufacturing processes.
At the heart of our commitment is a dedicated R&D team relentlessly driving innovation, bringing state-of-the-art technologies to market. In an ever-evolving landscape, we strive to meet the dynamic needs for speed and efficiency. Explore the pinnacle of bioseparation excellence with Astrea Bioseparations, a Biotage company, where every breakthrough propels us towards a future of enhanced patient care.
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Featured
Lentiviral vector purification tools, for high recovery of LVV.
Key Features
High infectious lentiviral vector (LVV) recovery with LentiHERO® is achieved by:
- Low salt elution – elute in less than 50% salt concentration used with other products
- Low shear environment – 860 nm mean flowpath diameter, no dead end channels combined with dual direction flow
AstreAdept® LentiHERO® formats of 1 ml and 10 ml bed volume enable precision scaling:
- Stay radial – our small radial capsules are available in 1X and 10X formats accommodating 1 ml and 10 ml bed volumes, respectively.
Extracellular vesicle isolation capsule for high recovery of EVs, including exosomes, 1 mL and 10 mL bed volume.
Key Features
- High binding capacity, equivalent to 1.2E+12 viral particles/mL adsorbent
- High recovery due to mild conditions
- Fast processing
- Sanitizable with 0.5 M NaOH
pDNA polish, at low operational pressure, after AEX primary capture or linearization of pDNA.
Chromatography capsule containing a hydrophobic AstreAdept® nanofiber matrix designed for removal of impurities after AEX primary capture of pDNA or post pDNA linearization at process development scale.
Key Features
- High dynamic binding capacity
- 4 mg/mL adsorbent, (4.7 kb) pDNA sequence
- Low operational back pressure due to open unobstructive flow path
- Suitable for large plasmids (tested up to 34 kB)
- Sanitizable with 0.5 M NaOH
Evolve® Process Columns have been designed specifically for use in biopharmaceutical applications. Available in eight diameters, Evolve® Process Columns provide cost effective, scalable, high performance technology suitable for use in both pilot and production scale chromatographic processes.
Optimize your chromatographic processes with our Evolve® Refresh Kits, designed for quick, single-use applications and to prevent cross-contamination in all Evolve® Process Columns.
Mixed mode resins for the removal of HCP, light chain IgG and high molecular weight aggregates
Endotoxin removal affinity adsorbent