Lentiviral vector purification tools, for high recovery of LVV.

Key Features

High infectious lentiviral vector (LVV) recovery with LentiHERO® is achieved by:

• Low salt elution – elute in less than 50% salt concentration used with other products
• Low shear environment – 860 nm mean flowpath diameter, no dead end channels combined with dual direction flow

AstreAdept® LentiHERO® formats of 1 ml and 10 ml bed volume enable precision scaling:

• Stay radial – our small radial capsules are available in 1X and 10X formats accommodating 1 ml and 10 ml bed volumes, respectively.

Extracellular vesicle isolation capsule for high recovery of EVs, including exosomes, 1 mL and 10 mL bed volume.

Key Features

• High binding capacity, equivalent to 1.2E+12 viral particles/mL adsorbent
• High recovery due to mild conditions
• Fast processing
• Sanitizable with 0.5 M NaOH

pDNA polish, at low operational pressure, after AEX primary capture or linearization of pDNA.

Chromatography capsule containing a hydrophobic AstreAdept® nanofiber matrix designed for removal of impurities after AEX primary capture of pDNA or post pDNA linearization at process development scale.

Key Features

• High dynamic binding capacity
• 4 mg/mL adsorbent, (4.7 kb) pDNA sequence
• Low operational back pressure due to open unobstructive flow path
• Suitable for large plasmids (tested up to 34 kB)
• Sanitizable with 0.5 M NaOH