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- LentiHERO® - Lentivirus Purification
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- Nereus LentiHERO®
Nereus LentiHERO®
Purification of lentiviral vector feedstocks at lab-scale.
Key Features & Benefits
- High binding capacity of 4.7E+10 lentiviral particles per unit
- >60% recovery of lentiviral particles, tested in serum-free feedstocks
- 95% reduction in HCP contamination
- Lab-scale purification of lentiviral particles in 5 easy steps
- Mild process and elution condition
Technical Data
Feature | Description |
---|---|
Binding Chemistry | Weak anion exchange |
Typical Model Protein Dynamic Binding Capacity | >Bovine serum albumin at 1mg/mL in 10mM at Tris pH 8, >60 mg/mL |
Recommended Maximum Capacity per Device | 2E+10 viral particles |
Options for Loading | Benchtop centrifuge, Vacuum manifold |
Equipment for Elution | Benchtop centrifugation |
Maximum Volume per Centrifugation Load Based on Centrifuge Type | Swing out: 15 mL, Fixed angle: 12 mL |
Additional Equipment Required for Purification | 50 mL centrifuge tubes with filter caps |
Recommended Operational Centrifugation | 1000 x g |
Chemical Stability | Compatible with buffers commonly used in bioprocessing, including 20% EtOH, 1M acetic acid, 0.5M NaOH, and solutions containing up to 10mM EDTA |
Connections | Luer |
Intended Use | For research use only |
Compliance of Performance and Identification | Each product has passed a flow test and an inspection test. |